ISSN 1119-4618
 

Original Research 


EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS

Misbahu Sambo, Abdulqadir Yunusa, Atiku Muhammad Kano.

Abstract
ABSTRACT
The aim of this study was to investigate the effect of controlled-diet in the treatment of rats with hepatotoxicity caused by CCl4. The serum level of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, direct bilirubin, and total bilirubin was measured using standard methods and compared among group I (Normal control), group II (CCl4 control; hepatotoxic rats without treatment), group III (Hepatotoxic rats treated with 5.2 mg/kg of standard drug only), and group IV (Hepatotoxic rats treated with 5.2 mg/kg of standard drug + controlled diet). The result showed that the level of the biochemical parameters was significantly lower (p < 0.05) in group III compared with group II. However, the result showed no significant difference (p > 0.05) in the level of measured biochemical parameters between groups III and IV. These results reaffirm the hepatocurative effect of the standard drug (Livolin). It also indicates that the controlled diet used in this research has no positive (curative) effect in the treatment of liver disease.

Key words: Key words: Carbon tetrachloride, Controlled-diet, Livolin, Liver disease


 
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How to Cite this Article
Pubmed Style

Sambo M, Yunusa A, Kano AM. EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS. JPAS. 2018; 15(1): 18-22. doi:10.5455/sf.10243


Web Style

Sambo M, Yunusa A, Kano AM. EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS. http://www.atbuscienceforum.com/?mno=10243 [Access: December 12, 2018]. doi:10.5455/sf.10243


AMA (American Medical Association) Style

Sambo M, Yunusa A, Kano AM. EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS. JPAS. 2018; 15(1): 18-22. doi:10.5455/sf.10243



Vancouver/ICMJE Style

Sambo M, Yunusa A, Kano AM. EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS. JPAS. (2018), [cited December 12, 2018]; 15(1): 18-22. doi:10.5455/sf.10243



Harvard Style

Sambo, M., Yunusa, . A. & Kano, . A. M. (2018) EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS. JPAS, 15 (1), 18-22. doi:10.5455/sf.10243



Turabian Style

Sambo, Misbahu, Abdulqadir Yunusa, and Atiku Muhammad Kano. 2018. EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS. Science Forum (Journal of Pure and Applied Sciences), 15 (1), 18-22. doi:10.5455/sf.10243



Chicago Style

Sambo, Misbahu, Abdulqadir Yunusa, and Atiku Muhammad Kano. "EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS." Science Forum (Journal of Pure and Applied Sciences) 15 (2018), 18-22. doi:10.5455/sf.10243



MLA (The Modern Language Association) Style

Sambo, Misbahu, Abdulqadir Yunusa, and Atiku Muhammad Kano. "EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS." Science Forum (Journal of Pure and Applied Sciences) 15.1 (2018), 18-22. Print. doi:10.5455/sf.10243



APA (American Psychological Association) Style

Sambo, M., Yunusa, . A. & Kano, . A. M. (2018) EFFECT OF CONTROLLED-DIET IN THE TREATMENT OF CARBON TETRACHLORIDE-INDUCED HEPATOTOXIC RATS. Science Forum (Journal of Pure and Applied Sciences), 15 (1), 18-22. doi:10.5455/sf.10243